After taking an estimated 7200 pain pills over 2 years. He finally said that it was time to start looking at a nerve pain medication. (I love my doctor he is the one that diagnoised my back issues he even had a tears in his eyes) He mentioned neruontin for nerve pain and then started talking about antidepressants I jumped in and said that is what I want. And something to help me sleep. He then said cymbalta. I tried it last night with everyone telling me it would knock me out. Well I was up till 2am and had some mild side effects but want to know how long did it take you to adjust to the medication? I am only on 20mg. My eyes don't want to focus but other than that my mind feels good. Oh the best part last night as I cuddled under the blankets I could feel them my blankets that is my legs were no longer numb. kind of excited but nervous with new meds.