Large stitch quilting is very much like the Japanese Sashiko style of quilting. I think it gives a quilt an ethnic appeal - especially if bright coloured threads are used. If you are interested to try big stitches on your quilt, why not have a look at the Indian style of embroidery called Kantha? That style of stitch on your quilt could look extremely attractive if used correctly and in moderation.
Here is a link to a kantha stitch site - a clever quilter could adapt these designs to suit a casual throw: