I have both and use them for different things. The Go is good for cutting squares, triangles, etc where you do not want to have fusible on the back of the fabric.
The Cameo is great for cutting applique shapes. If you do machine embroidery applique, the Cameo is fantastic. You can use the embroidery design to get the shape into the cameo and have it cut for you. I bought my Cameo after seeing this post.
http://terrijohnsoncreates.com/2012/...lique-designs/

I agree with alikigirl - the Cameo requires fusible on the back of the fabric in order for the machine to cut (and a computer connection), whereas with the GO, you just put your fabric on the die and run it through the cutter. I have the Cameo and I have the Accuquilt Studio cutter, and the Cameo is only productive for cutting applique shapes (or paper/vinyl crafting) - not cutting large volume block pieces. It is basically like a Cricut machine without the need for cartridges as the designs are sent from your computer to the Cameo instead of from a cartridge.

If you plan on using it mostly for cutting strips, have you ever considered the Shape Cut ruler? I watched the demo for a Go and the lady was going to cut fabric for a log cabin block. First she took 2 rulers to square up the fabric, then she went and put it in the cutting machine and cut the strips. As I watched, I thought how much faster I could have cut the same strips using the Shape Cut ruler. Another reason why I don't buy the Go cutting machine and others like it, is because if I'm cutting strips I use the Shape Cut and then use specialty rulers like Phillips Fiber Art's Squedge rulers. Will you be using this ofter enough to justify the cost? Good Luck.

Also with the go and studio you can cut lots of layers out so you get it cut fast. Depends on what you are wanting I guess. I have the studio and would not trade it for another type. However the Cameo may have something you like.

Because of my hands I don't use a rotary cutter much. So the studio worked for me the best.

I purchase a Fabrique fabric cutter for applique shapes. I worked but found out it would only work well with their stabilizer which was very expensive. As a result I don't use it much. Not happy with that! Don't know about Cameo

I don't like the fact that the Cameo requires the fab be backed w/stabilizer-interfacing. Sounds like way too much work to get a results. I have a GO, never regretted its purchase......cost of dies may be a deterrent to some but in comparing cost of blades of rotary, time saved, stress on hands/shoulders, accuracy....cannot be beat....IMHO

I do not have either But I do have June Taylor's pro shaper that cuts 2.5" sets. I can cut a yard in seconds. I got it at JoAnn's.

That's what I don't like also, BUT the design possibilities are endless. Not only can you design your own shape if you want (or download from the internet, etc) you can cut it in any size you want up to about 11" or a little more or as little as an inch or less. That's the big draw of the Silhouette. So there are pros and cons to each. Since I papercraft I have both (and a regular size big shot too-it's a disease) so I'm fortunate to be able to take advantage of the pros of both.

I thought this was interesting, using starch rather than interfacing to cut fabric with the Cameo! As has been pointed out it really depends what sort of cutting you would do most often.

http://thereshesews.blogspot.ie/2013...cameo-yes.html