Yes, 50/3 is good to use for piecing. With whatever thread you use do a test and verify that it doesn't throw off your seam allowance. Thicker thread takes up a tiny bit more room & vice versa.
Achieving an Accurate 1/4" Seam Allowance
Also there has been a lot of discussion lately about the use of poly thread. Evidently most people feel it's just fine to use in quilting due to improved quality.




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