Choose a backing slightly larger than your top. Batting is optional. You can use cotton, homespuns, flannel.
My post used 4 preprinted Teddy Bear panels.
http://www.quiltingboard.com/t-132924-1.htm
Line up your panels so that all the print is in the same place. Choose several spots and put a pin through all the layers checking to make sure it is in the same place on all 4 pieces. (It helps to put pins in several places so it doesn't shift. Lay the top on the backing (and batting if you choose).
If using your sewing machine, draw a line on the diagonal at a 45 degree angle. Stitch lines on both sides the desired width. I used the Olfa Chenille cutter, and choose the 3/8" size. Once all the lines are stitched, use the cutter to cut in the middle of the channels. You will be cutting through only the three TOP layers. The fourth panel/layer will remain uncut.
Tip: It helps to cut the 4th layer slightly larger than the other three so you have somewhere to slip your cutter into. Otherwise you are peeling back and hoping not to cut the 4th.
Trim your piece and apply binding. Wash and dry.
If using the long arm, load a large backing, layer all your pieces and pin. Float the top on the diagonal and stitch straight lines.
Here is a great tutorial with photos. Any questions, feel free to ask.
http://www.aestheticnest.com/2010/08...ille-baby.html