I learned this the hard way...I sewed a whole bunch of 44 inch strips together, one to the next. I did notice that they weren't ending the same, even though they were the same length, but I was new to quilting and just forged on. When I was done (sewing all those expensive batik flannel strips), I had a big curve in the middle, and the piece was unusable. I think, after tossing it aside for some years, I finally cut it into a big fish shape to make a big floor pillow, but I don't know if I even finished that. So depressing.
Good for you for thinking this out and asking about it!