What about a variation of an "I Spy" kind of quilt showing pictures of things that she likes to do (hobbies, etc) or places that she has visited or would like to visit. If I was going for regular chemo treatments, I would be more comforted by something that would truly put me in my happy place. A quilt containing pictures from "happy" moments in my life would give me comfort and joy during such a difficult time. If she enjoys gardening or cooking, you could use fabric the represents those hobbies. Maybe her family could help by providing some "fun" pictures to use in a quilt.