We are on our 4th RV and we both dread the day when we feel uncomfortable driving with one. We have had 2 travel trailers, and now are on our 2nd fifth wheel. We used to go on weekend trips all the time when we were working, along with several long weekend trips a year and one or two week long (or longer) trips a year. Now that we are both retired, we go camping from Sunday or Monday through Wednesday or Thursday. The Ohio State Park camping fee is half price for senior citizens on Sunday - Thursday nights. We are planning an extended trip to the southwest sometime this year. We just love being in our RV and have been out camping during every month except January.
Advice? Here are a few things to consider
RV mattresses are usually very uncomfortable. Plan on probably having to buy a good mattress for your RV.
Most RVs now come with slideouts that the RVs much more spacious and comfortable. One thing we watched for when we were looking for our newest one was that you still had access to the bathroom and the refrigerator when the slideouts were in. That way on the quick road stop, you can still use the bathroom and have access to the frig for a quick lunch or a drink without having to open the slideouts out.
Someone here mentioned that the max length for many state and national parks is around 30 feet. Good thing to remember, depending on what kind of campgrounds you will like to stay at. There are many different styles of campgrounds, from extremely fancy, expensive, snooty places that have everything you could imagine and that will even park your RV for you, to primitive places where you will have to bring your own water in and you will not have any electricity. (There are always generators, but they are noisy and expensive and restricted in many places.) You can pay anywhere from over $100 /night to less than $10/night. We average about $25 - $30 / night.
A motor home is nice because you have only one vehicle and you do not have to tow anything behind you. It is generally easier to drive. However, if you have a fifth wheel or a travel trailer, and you find you need a loaf of bread and a gallon of milk, you do not have to pack up everything, unhook from the water and electric to drive into town to go to the grocery store or to go out to eat or do your sightseeing. You will have your tow vehicle (usually a pickup truck) to drive around in without packing up a motor home. Another alternative which many do is to tow a small car behind a motor home so you have a vehicle to drive around with.
And yes, I always have a sewing machine, fabric and all sewing and quilting supplies in our camper!
These are some main considerations, but I am sure there are many more! If you have any specific questions, please feel free to ask! Have fun!