I have great luck with a product called "Restore" sold in most quilt and fabric stores. I just wash on the hand wash cycle in cold water (saves having to wring the quilt). However, be careful with the vibrant red. You might want to test it's color fastness with a damp white cloth of some kind (tea towel, wash cloth, etc.) before you wash it. However, I always use a shout "Color Catcher" or two when I pre-wash my fabrics, they really do work. I just bundle all the colors together in the machine and let the color catcher do its magic, so if the red is not colorfast you could even add one to the water in the tub.