I used to be a heavy smoker, but did not smell the "smoke" until I had quit smoking. Since my sewing area was in my bedroom, there were few opportunities to air out the fabric. When I started to quilt, the smell bothered me so much that I had to wash all the fabric before I could use it; but just a regular wash cycle seemed to get rid of the smell. I'm not sure how you could "wash" bolts of fabric but airing the fabric outside is a good option. I remember my Mom putting sheets on the line, even in winter, then bringing the frozen sheets in to finish drying, as they smelled so fresh from being outside. Give Mother Nature a chance to get rid of the smoker's smoke in the fabric first, then I would wash it with possibly a mild detergent with a pleasant scent to help get rid of the odor.