I have made two quilts using flannel, that I can remember. The first was my very first quilt ever - I did not prewash and used 1/4 inch seams. It used three inch squares in a trip around the world, baby quilt. I used warm and natural and flannel backing. I made it for my granddaughter when she was born and she still uses it and she is 11. The second was a flannel and chenille half square triangle quilt for the 6 year old grandson when he was born. Still uses it. Prewashed, used 1/4 inch seams and flannel batting and backing. I didn't have any trouble with the 1/4 inch seams and these quilts have been washed a lot of times and are still going strong.