cjsews has pretty much the system (if you want to call it that) that I use when picking fabrics for a quilt. Start with a great print, then if you don't feel comfortable picking colors, look at the selvedge of that great print and you will find circles of all the colors that were used in that print and choose from that pallet and you can't go wrong. I've been told that I have an eye for color, but using this method, people will say that you do too.