Splinter

I prefer working with scraps to working with yardage. I also usually work with fairly small scraps. However, I think my process will work with larger pieces if you prefer.

Pick a simple block and start sewing the leftovers accordingly. Nine-patches and four-patches go well together. You can use a more complex block if you choose. Once you have enough blocks, you can sash them all with the same fabric or put an alternate block between them. Using this method, have this in progress.
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Most of the scraps are from a quilt that was made with one line of fabric by Moda. Because so many of the scraps came from a coordinated line, the pieces that don't match still seem to coordinate. It also helps that I used such small pieces.