There are lots of patterns out there for I Spy Quilts. If you're making it as a baby quilt, I think you'd just make it smaller. Your design depends on how much time you have to spend on it. My cousin is making one of the most gorgeous (and difficult) ones I've ever seen; one each for her 2 grandsons. (I wouldn't get that one finished in my lifetime.) They are about 3" fussy cut hexagons with little red triangles between them.
This one is cute, it's a Jenny Doan video
https://www.youtube.com/watch?v=tvqPnoiLSV0.
This one is cute, too
http://www.all-about-quilts.com/joan...ns-week15.html.
This is the favorite that I've made so far. It was easy. I made it in strips instead of a disappearing nine patch, as matching was easier for me.
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This my next one:
http://saneandcrazy.blogspot.com/search?q=abc
bkay