When I want to get rid of something, I either think about how someone else will love it far more than I do, or I picture the executor of my will rolling their eyes and saying, What on earth did she keep that for?
I did an almost complete cleanout when we moved as we were going to a furnished condo. It is a very freeing feeling to get rid of so much stuff.
If there are sentimental items, take pictures of them, keep the pics, donate the items.