I think leave it 'as is' - unless the couple you are making it for specifically asks to have her name removed.

Then, I think I would applique a small something that would fit over the name. Might be necessary to applique a few other things here and thee then to make it look 'intentional'

Sometimes trying to remove ink makes a bigger mess than leaving it be.
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You could ask the man if he would like his "ex" name to remain on the block, and if not, ask him to rewrite his block. It isn't that difficult to pick those stitches out & inset a new block.

That happened in my family too, we just left the name on.

agreed....just get a new block made and replace

I think I would just leave the name on. The wishes were from the both of them.

I would leave it.

I would just leave it as it is!!!!

The signers should have no say in the matter, the quilt is not for them and it's certainly not the only time their names will be linked "on record". Since the husband was the 'friend', he's the one who probably wrote the message...maybe even signing his wife's name.

Leave it be. If the wedding couple doesn't want her name there, they can either fix it themselves or ask you to do something about it later. Chances are, more than one couple will separate in the next 25 years anyway.

I would ask the couple, before doing anything.

If you really must cover it, why not applique something on that square.