Disappearing ninepatch would be my first choice. Second would be a strip pieced trip around the world. Whatever you choose will be great with your fabric choices!

I think the warm wishes with the bares in the middle

Congratulations Grama!! I think the warm wishes would be cute too :D:D:D

Thanks all of you! Not ready to start it just yet, have a couple christmas things to finish! Thinking of warm wishes with a border of pinwheels?