I have made three quilts using old clothes. I recommend making a crazy quilt. This way you can use everything. The more textures and colours you use the more interesting your quilt. Make sure you wash everything! You can use an old sheet for your foundation for your blocks. The thrift store is also a good source. Just make sure it's really thin. Sorry I can post my pictures as I don't have them with me.

Here's two memorial quilts I've made from my mom's clothes. I wasn't sharp enough at the time to get dad's clothes when he passed away - so we added the only thing we had...a sweatshirt jacket (I still regret not getting his clothes). This one I gave to my brother - simple, not "girlie". I also used this same pattern for my aunts (her sisters):
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And this one I gave to my sister:
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The flowers are made from dad's sweatshirt in my sisters and the blocks surrounding it are mom's clothes. The rectangles were from her jeans. I incorporated the sweatshirt into the center blocks in my brother's.

Cindi - they both are beautiful! I haven't thought of doing that until this thread. Thankfully my parents are still both alive and doing well in their mid-80s. TFS!

I had a friend that made a quilt from her brother that passed away shirts. She just cut the front into about a 10" block, leaving the buttons and the front pocket if it had one on it and sew it together with a sashing in between. It was very nice

Cindi, those are beautiful!

Here's a quilt my sister and I made with our nephew's shirts and pants. His son loves it.

I made one for my aunt who is 90 yrs old now when my uncle (her husband died) he was 96yrs old. I made it out of his old jeans. It's a rag quilt with flannel on the back. I embroidered their names, along with their children, grandchildren and great-grandchildren names on it. She is the one who inspired me to quilt. She hand pieced and hand quilted all her quilts. She loves it and shows it to everyone comes to her home. It is my avaitar.

Clothing quilts
 

I made 3 small quilts from a lady's clothing. Stretchy walmart pullovers, denim shirts with embroidery, and lightweight jeans (stretchy)

cut sections from clothing ( bigger than the size square. Use very lightweight stabilizer and iron piece onto stabilizer. Cut your block . I pieced some to make the fabrics go further. I left the collars and buttons on. You can sew them together with or without sashing, but if you use sashing, put stabilizer on it too so all pieces fit right. I quilted manually on my longarm, just outlined all the collars and buttoned fronts. And then freehanded rest of it. Came out very nice! You CAN do it! Keep in mind it will be heavier so make a smallish one if you can........Good luck!!!

When my stepson died some of his clothes were made into cambray bears. His mom got his cowboy hat, which she keeps in a plastic bag, so that she can pull it out and still smell her son. We forget how very personal these items are and how they are such a touchstone to the one that is gone. The cambray bears were appreciated, but family members would have prefered them, unwashed, before it was made.

I recently made a memory quilt using the Warm Wishes pattern, very easy, but effective. I used neutral black and grey for the strippy blocks and the clothing squares for the squares. The clothing was made from various fabrics so I stabilized them all with a lightweight woven (yes, woven, because it's softer) stabilizer.