I think you have to decide which is more important to you -- having an antique given to you by a friend or using an antique quilt given to you by a friend. If it will only be a possession that you will store, then I say leave it in it's present condition. If you want to use it or have it on display, then I say make hand repairs that will add to the longevity of the quilt. Remember, her intention was that you would make the repairs.