Both the guilds I am in make what are called "Quilted Hugs" -- these are quilts that are donated to the local hospitals (used to be called ABC Quilts under a national umbrella but it went under) for their preemie units. The quilts are put over the isolets, then go home with the babies. We have a guild "collection day" once per year when we get a ton of them all at once, but many of the ladies donate all year (and don't "save" them up). These quilts are at least 36 x 36, and don't vary too much from that size.
A BOM group I've been in for a while started this year off making blocks for larger quilts which we will donate at year's end to a local shelter or to Ronald McDonald House. We are using the "wonky star" block which is very easy and quick, and one of the members has committed to putting the blocks together and doing the quilting by the next month's meeting. They look great!