PuffinGin, this is manageable, one step at a time. I'd suggest take laundry items to laundry room (or where it's out of your sewing room), work on your immediate items, then go to organizing & work in the laundry in between. Also, please make a list & work on sections, before long it's all done. Buy more bins if you need to, or a shelf, then you won't feel closed in. Good luck & show us your finished projects. You can do it.
I had both knees replaced last July, then more medical problems, so just got to shredding old papers I'd stuffed in my big closet, started doing a few exercises, & now I'm ready to start sewing/quilting soon as my Viking gets back from the dealer (cleanup).