I do know for a fact that you HAVE to get a special fabric that doesn't let the tips of the feathers poke through - it is very tightly woven - for pillows it is called "pillow ticking". As with another poster - you would surely have to sanitize the feathers first - not sure how you would do that - maybe search the internet for that. I think that it was be a very big job to get enough "good, clean" feathers gathered up to stuff a quilt with them.