I am currently working on an ex large queen quilt. All the quilts I have made, have been tied, Can't afford a quilting machine.
I use crochet cotton, can get many different colors, to match/or accent your quilt
I use a surgeon knot.
I cut the threads, shorter on a baby quilt and longer on any other.
Does not matter the size of the quilt. I guess you might say, how much time do you wish to spend tying. I don't mind, a little here, a little there and it get's tied