I'm sure smokers don't realize how awful it smells. Sometimes a family member of a patient reeks of smoke, and I feel sick the whole shift at work. Then they act surprised when they get instructed on the dangers of second hand smoke to newborns by every nurse and doctor, like "how did they know?". So I doubt they realize. I don't even wear perfume to work for fear of annoying others. My brother just quit after 18 years and I still tear up saying so, like I've been given more years with him, God willing. I'd wash the quilt, try to hang it outside, maybe pack it in a box with odor absorbers. Sorry for your dilemma, good luck!