Julie, I have the same problem with the corners of my thumbs cracking with deep crevices. It hurts so much and constantly have bandaids on them. The only thing that I find heals them is the Neosporin. I put it on at night and cover with bandaids. I remove the bandaids in the morning and keep them off until nighttime. I also use rubber gloves when my hands are in water. I like the other suggestions that the girls had and I think I will try some of those lotions.