It depends on what the poly to cotton ratio is... if its 30 percent poly I will use it in quilting .... if its 70 percent poly its a garment only or home dec . .. as I am really obessed with pressing and LOTS of steam when it comes to quilting... and high poly content does not lend itself to that kind of treatment.
Sometimes there are great prints that have some poly ... and I just can not resist.
I reciently saw a quilt made from all poly /cotton blends it was fabulous and you would not know by looking at it that it had blends.