My personal approach is that if there is not a thank you nor an acknowledgement of some kind, then there is usually no more gifting. If there should be a subsequent gift for any reason, it is usually small and inconsequential by comparison.
If ever the lack of or a lesser gift is mentioned (hardly ever by the recipient, but usually a relative who may have been asked to mention it), I will inform them something to the effect that because I never heard a thing about the earlier gift (usually a quilt in which I gladly invested a lot of time and expense), that I thought they simply didn't care for it.
I don't give gifts for the thanks to be returned, but I also don't do rudeness nor disrespect - at least not a second time.