I would thank the person who made it and probably keep it on the bed in the spare room; I love hand made gifts and appreciate the effort and time that someone spent in "thinking" of me.
My step son (who lives with us) has burned holes in my sheets and comforters, and has never washed his bedding for the year he has been here. When we move (no HE IS NOT moving with us I draw the line here) I will keep that bedding to put on the bed if/when he spends the night. I would not even put a quilt that I did not like on the spare bed when he is there. At 28 there is no excuse!!!!!