I don't have arthritis but I've got a lot of old sports injuries (on top of being heavier than I should be...). I get up on a regular basis and refill my coffee or grab some water, maybe iron something really quick... My husband appreciates that I come out of my hole for 5 minutes to give him a kiss every 40 minutes or so and I don't get so stiff. I heard of one gal that used a digital timer to make sure she spent some time with her family and didn't just let her day run away with her. I watch Netflix while I'm working so, when an episode of whatever is over, I know it's time to take a short break if I haven't recently.