I picked the 12 ft frame for 2 reasons. Largest I could get in my room...and I dont' want to make quilts so big I need a 14 ft table. I picked the 22 inch over the 26 inch because my Gammill before had a larger throat. When I got to the back of the quilting area, I bent at the waist to reach. Every time I did that, I tweeked my back. I would rather roll more than not sleep well with a tweeky back. 12 frame w/ 22 in throat was right for ME. What will be right for YOU?
PS try as many as you can. My Innova, Jane, is very lightweight and I have no problems using what ever thread I like to try.