I'm not 100% sure this is what you are looking for, but "Setting Solutions", by sharyn craig, is a wonderful resource on setting blocks, especially blocks that may not all be the same exact size, like sampler blocks or those that came from a block exchange. Amazon lists some used copies.
http://www.amazon.com/Setting-Soluti...s+sharyn+craig
Another alternative would be to get Electronic Quilter (EQ7). This will let you design blocks, clone them and then play with the layout. You can also just use a draw or paint program, but it's a bit more fiddly than EQ7.