Your difficulty will be when you are working in the centre of the quilt, trying to get it all in your harp space and then actually stitching it with any sort of control. One teacher suggested to me to add the batting in sections rather than all at once. For instance add the batting to the centre area of the quilt lengthwise, baste it and quilt it, but leave yourself room, I.e. Don't stitch right to the edge of the batting, so you can add batting to the edge on either side and join it to the first strip of batting, baste it then quilt it. Then do the third strip on the other side. That way, you are only having to put the quilt top and backing into the harp of your machine, with a little bit of the centre while you quilt the centre area. A walking foot is also extremely helpful to get even feeding of your layers, if you have one or can get one. If you don't have your quilt entirely pieced together, you can also make it and quilt it inspections and join the sections later when it's already quilted. Good luck!