I think the little pink quilt shop in this youtube clip of the flooding from Hurricane Irene might have been the original A Notion to Quilt that is now safely located high and dry on MA Route 2. Strictly speaking, it's not in the Berkshires, but is in Franklin County, close enough. These beautiful mountains belong to all of us.
https://www.youtube.com/watch?v=_NWDRyg1j88 Another great quilt shop, not in the Berkshires, but just north a little into Wilmington, VT is the Norton House which was also devastated by Irene, but it, and many of the businesses in historic buildings on the riverside cleaned up and reopened in the same locations. What a task!
https://www.youtube.com/watch?v=hvVMOoR93_c