I have to go every 6 months for a cleaning -part of my after care from my transplant and when I suggested using an otc treatment for in between appts he kinda hit the ceiling-- just because the ads on TV say dentist approve these things does not make it true. They create more problems to your teeth and gums. And they can alter any prescribed medicines that we have to use. So check with your dentist-your family doctor and even your pharmacist for interaction problems with these treatments before using them. Be safe not sorry--