My aunt told me the imperfections is how you know it was handmade.
As I thought about her words, I realized the imperfections tell a story. See a stitch that wandered? Maybe the person took their eyes off their work a moment to give their child or grandchild a quick kiss on the forehead.
A seam doesn't line up? Maybe their spouse bumped into them as a prank to have fun with them. Or their concentration was broken by them thinking about something or someone.
Imperfections are stories and are why handmade quilts are much more charming than mass produced machine made quilts.