I think that it is a matter of where you will place the machine and where you have room for extra tables.
When the machine is oriented facing you, the quilt is to your left and right.
When the machine is oriented as a normal sewing machine, the quilt is to your left and in front of you.
I chose an APQS George and kne reason was that i needed to have the bulk to my left and in front of me rather than in one plane to the left and right.