I made a memory quilt for a friend of mine whose father passed away & used some of his shirts for it. I couldn't decide on a pattern. So I decided to try something related to the state he was from. He lived in Indiana so I made the Indiana Puzzle Block pattern from Quilter's Cache.
http://www.quilterscache.com/I/IndianaPuzzleBlock.html
I made it on point & it turned out really pretty & my friend loved the fact that the block was related to his home state.