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I think you need to be very cautious if you do this. My Granny made me this quilt of mixed fabrics and I'm having some problems with it. And it's less than 50 years old! (though I must confess many of the fabrics are probably much older) Tongue is very firmly planted in cheek - prewash as many here have advised and make the young man a 50-year quilt.
I can't wait to see it finished!