You will need a walking foot to sew straight lines across your quilt. You shouldn't have to change any settings on your machine, but make a small "sandwich" and test it until you have it right.
Polyester wadding is fine but keep in mind that it is puffy. Do not wash it first. Cotton works well and I think it's easier for a beginner to quilt through.
The package will tell you how much room you can leave between lines, but I think an inch or so is about the widest. I use painter's tape to make guidelines. Make sure you baste your three layers very, very well. I use large safety pins and remove them as I go. When I was just beginning, however, I used fusible wadding - you iron it to hold it tight. There are lots of you tube videos online to give you hints. Good luck!