I'm basically a hobbiest quilted with a 12ft/26" machine. I quilt mostly for myself but occasionally for a friend if they bend my arm. True, my sewing room is getting crowded but I have no where to store the system if I did take it down plus it has robotics so I don't want to mess with those wires. I've put all my cables/cords strung up on the rafters so I won't trip over them as I have all my threads on the wall behind the frame. Plus I've got a lot of tubs and rolling carts under the frame as that's a great place to store stuff.
Taking down and putting back up a quilt system is harder than you can imagine with all the cords, wires, etc. Better to find a good spot for it and leave it there. If you're short on space, you might think about putting it on locking wheels so you could push it up against a wall when not in use. The locking wheels is because you don't want it moving on you as you quilt and keeping the frame/machine level is a must in most cases.