I work full time and take call 1-2 nights a week - so some of my off time is spent sleeping!
There is a sewing machine in our call room, so when things are quiet I can sometimes get a lot done there with no distractions. Home is hit or miss depending on what else I need to get done - laundry , house keeping, spending time with 2 kids 9 and 10 and husband. I'm not a good multitasker - I can't do much else when I quilt, and I have a hard time just quilting for a few minutes - but some one suggested just doing one block, or part of a binding. I'll try that. Weekend quilting getaways let you get a lot done with no distractions, and get me inspired by seeing what everyone else is doing. I try to do 2 a year. Your LQS may have some planned.