I sewed clothes before I took up quilting. It is different in that the patterns can be hard to read sometimes. I find that if I start getting frustrated I put it aside for a while and when I come back I can normally figure it out. As others have said the pattern sizes do not correlate to clothes size so make sure that you fit the pattern to yourself. I find that I am often three different sizes on the patterns with a dress. Like I said it is different but I don't think harder - if you can quilt I am sure you can make a dress. Have fun with it and if you start to get frustrated just stop for a while!