Just like Mar32428, I have the Janome 6500 and love the features she mentioned as well as the 'knot' feature at the end of stitching.
I did a bit of research b4 getting the Janome but the larger throat/neck area was what sold me cuz I hate trying to stuff a quilt for quilting in a smaller area.
Previously I had a Kenmore for over 35 yrs so I wasn't loyal to any particular brand.
As others have said, do your research, try out different brands and choose the one that is right for YOU.
good luck and happy quilting! ... sue