amma is exactly right, look around for "helper tools" I have shears not scissors, Friskars makes the pair I have, which is endorsed by the Arthritis Foundation, they are spring loaded so no "thumb" work. But as Janeen said rotary cutters, whenever possiable. I'm sure they have some that "feel good" in your hand. And here's a tip, Joann's is GREAT about returns. If it's comfortable in the store but not at home, take them back right way. Don't live with the ones that hurt!~ :D
I've found cutting and ironing/pressing is the worst for me. I'm not to the point that I'm looking for a lightweight iron, but I'm sure I'll get there.
Hand sewing is out for me. Oh my, hand sewing gets me so bad I can't do anything with my hands for at least a week, and then it's special meds ect. I CAN sew on a button or two. But I don't like to push it.