I don't iron it to crease it, but I do iron it as though I was pressing a seam. Usually I sew the binding to the front and hand sew to the back. So what I do is put the quilt face down on the ironing board and gently pull the binding out straight while ironing. After I press, I use the binding clips to hold the side I'm working on. It seems easier to keep the binding from turning back away from me that way.