In my first machine quilting class I learned that you need to "stabilize" the quilt with evenly spaced stitching across and down the middle and the edges. Then you keep dividing it up into smaller sections and then it's much easier to look at just that section and do loops or meandering, to me the stippling where you don't cross a line is REALLY hard! It also helps to take a piece of paper and a pen and practice drawing designs in a continuous line as this reinforces the "patern" on you muscles. Most of all, do practice on a scrap sandwich each time before you start to quilt on the "real thing"
Jan