Yes, I sew barefoot or just with socks on. In my home, we usually take our shoes off when we come in from outside (we live on a farm). We got use to the idea from living in Japan for 5 years.
Even if I have shoes on for some reason (like in a class) , I take off the right shoe when I go to sew. I feel as if I have better control of the speed when I do that.