Theresa, the colored vinyl is easy to sew on, I just use a walking foot and a little longer stitch length. The clear vinyl "grabs" the foot and drags something fierce. It is "tacky". If you get a textured vinyl, it is very easy.
I design my own tote bags. I used a #9 needle, the same thing I use for piecing. Here is a pic, this stuff sews up like a dream, and NO hemming, just turn under the edge and top stitch!
http://www.quiltingboard.com/t-41912-1.htm