In a time long, long ago and a land far, far away...LOL...our grandparents and my parents used EVERYTHING! There is no reason not to use poly blends that I can think of. I use them because they are not as expensive and I have family (extended family) that will not take care of the quilts so I don't use expensive material or hand quilt them...I save those for myself or people I know will take care of the work and appreciate the effort and time I put into the project.