It would be tough for me to cut 6 layers at a time -- too hard to crank the fabric through the machine. From posts I have read, most people with the Go! limit themselves to 4 layers for most of the dies. The rag die has so many edges it is harder to crank through, so most people do just 1 or 2 layers for that die.
The Studio is very different -- much sturdier than the Go!